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[皮层强直后重排中细胞兴奋性变化与突触效率之间的相关性]

[The correlation between changes in cell excitability and synaptic efficiency in posttetanic rearrangements in the cortex].

作者信息

Kozhedub R G

出版信息

Zh Vyssh Nerv Deiat Im I P Pavlova. 1993 Jan-Feb;43(1):92-9.

PMID:8385404
Abstract

By calculating correlation coefficient (CC) was revealed the positive linear correlation between the changes of a direct and synaptic components of the pyramidal tract response pointing to the correlation between post-tetanic changes of synaptic efficiency and coincident shifts of cellular excitability. Values of CC calculated at initial stages of the trace process formation decreased afterwards and in an hour after the tetanic stimulation there was no significant correlation between the changes of components. Such temporary specificity in the association of the mechanisms under study permits to suppose the community of intracellular molecular substrate underlying interaction and manifestation of these mechanisms at certain stage of trace organization.

摘要

通过计算相关系数(CC),揭示了锥体束反应的直接成分和突触成分变化之间的正线性相关性,这表明强直后突触效率的变化与细胞兴奋性的同步变化之间存在相关性。在痕迹过程形成的初始阶段计算得到的CC值随后下降,并且在强直刺激后一小时,各成分的变化之间没有显著相关性。所研究机制关联中的这种时间特异性使得可以推测在痕迹组织的特定阶段,这些机制相互作用和表现的细胞内分子底物具有共同性。

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