Hutson W R, Wald A
Department of Medicine, University of Pittsburgh School of Medicine, Pennsylvania.
Am J Gastroenterol. 1993 Sep;88(9):1405-9.
A dual radioisotope technique was used to measure gastric emptying of a mixed solid and liquid meal in 30 obese (> 125% of ideal body weight) subjects and 23 age- and sex-matched nonobese control subjects. Gastroduodenal motility studies were also performed on seven obese and 10 nonobese subjects to compare postprandial antral motility. In addition, eight obese subjects underwent gastric emptying studies before and after substantial weight reduction (mean 8.3%). Gastric emptying of both solids and liquids was similar in obese and nonobese subjects, and antral motility indices did not differ between the groups. Gastric emptying rates before and after substantial weight reduction were similar. We conclude that neither gastric emptying nor antral motility appear to be abnormal in morbidly obese subjects; neither does gastric emptying appear to be affected by substantial acute weight reduction.
采用双放射性同位素技术测量了30名肥胖（超过理想体重的125%）受试者和23名年龄及性别匹配的非肥胖对照受试者混合固体和液体餐的胃排空情况。还对7名肥胖受试者和10名非肥胖受试者进行了胃十二指肠动力研究，以比较餐后胃窦动力。此外，8名肥胖受试者在体重显著减轻（平均8.3%）前后进行了胃排空研究。肥胖和非肥胖受试者的固体和液体胃排空情况相似，两组之间的胃窦动力指数没有差异。体重显著减轻前后的胃排空率相似。我们得出结论，病态肥胖受试者的胃排空和胃窦动力似乎均无异常；胃排空似乎也不受显著急性体重减轻的影响。
