Neumann R, Voss G
Experientia. 1977 Jan 15;33(1):23-4. doi: 10.1007/BF01936730.
Inhibition constants of several formamidines, their corresponding formanilides and other representatives of compounds derived from aniline, such as phenylureas, N-phenyl-carbamates and acylanilides, were determined for rat liver monoamine oxidase. The reversability of the inhibition and the lack of correlation between inhibition potencies and toxicities of the compounds tested add to the opinion that MAO inhibition is not a prominent factor in chlordimeform poisoning.
测定了几种脒、其相应的甲酰苯胺以及其他源自苯胺的化合物代表物(如苯基脲、N-苯基氨基甲酸酯和酰基苯胺)对大鼠肝脏单胺氧化酶的抑制常数。所测试化合物抑制作用的可逆性以及抑制效力与毒性之间缺乏相关性,进一步支持了单胺氧化酶抑制不是杀虫脒中毒主要因素的观点。