在受到杀虫脒或林丹中毒前后，飞蝗脑匀浆对色胺的酶促N-乙酰化作用（作者译）
[Enzymatic N-acetylation of tryptamine by brain homogenates of Locusta migratoria before and after intoxication by chlordimeform or lindane (author's transl)].
作者信息
Allais J P, Gripois D, Moreteau B, Ramade F
出版信息
Experientia. 1979 Oct 15;35(10):1357-9. doi: 10.1007/BF01964006.
PMID:91532
Abstract
Brain homogenates of Locusta migratoria are found to possess enzyme capable of catalyzing the N-acetylation of tryptamine. A main product of the enzymatic reaction is isolated and identified as N-acetyltryptamine by chromatography analyse. Both insecticides, chlordimeform and lindane, inhibit enzyme activity. A direct correlation between the degree of intoxication and acetylation of tryptamine is described.
摘要
人们发现，飞蝗的脑匀浆含有能够催化色胺N - 乙酰化反应的酶。通过色谱分析分离并鉴定出酶促反应的主要产物为N - 乙酰色胺。杀虫剂杀虫脒和林丹均能抑制该酶的活性。文中描述了中毒程度与色胺乙酰化之间的直接关联。
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[Enzymatic N-acetylation of tryptamine by brain homogenates of Locusta migratoria before and after intoxication by chlordimeform or lindane (author's transl)].在受到杀虫脒或林丹中毒前后，飞蝗脑匀浆对色胺的酶促N-乙酰化作用（作者译）
Experientia. 1979 Oct 15;35(10):1357-9. doi: 10.1007/BF01964006.
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Metabolism of biogenic amines in Drosophila nervous tissue.果蝇神经组织中生物胺的代谢
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