药物性天疱疮
Drug-induced pemphigus.
作者信息
Mutasim D F, Pelc N J, Anhalt G J
机构信息
Department of Dermatology, University of Cincinnati Medical Center, Ohio.
出版信息
Dermatol Clin. 1993 Jul;11(3):463-71.
PMID:8365032
Abstract
Drug-induced pemphigus is a heterogenous group of disorders in which a drug induces acantholysis. The majority of patients have immune features of pemphigus and have a course similar to idiopathic pemphigus. Few patients do not have a detectable autoimmune process, and their eruption usually resolves with discontinuation of the associated drug. The mechanism of induction of the autoimmune process and acantholysis is not clear.
摘要
药物性天疱疮是一组异质性疾病，其中药物可诱发棘层松解。大多数患者具有天疱疮的免疫特征，病程与特发性天疱疮相似。少数患者没有可检测到的自身免疫过程，其皮疹通常在停用相关药物后消退。自身免疫过程和棘层松解的诱发机制尚不清楚。
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