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亚硫酰氯诱导的肺损伤和闭塞性细支气管炎

Thionyl-chloride-induced lung injury and bronchiolitis obliterans.

作者信息

Konichezky S, Schattner A, Ezri T, Bokenboim P, Geva D

机构信息

Respiratory Intensive Care Unit, Kaplan Hospital, Rehovot, Israel.

出版信息

Chest. 1993 Sep;104(3):971-3. doi: 10.1378/chest.104.3.971.

Abstract

Thionyl-chloride (TCl) is used in the manufacture of lithium batteries, producing SO2 and HCl fumes on contact with water. We report two cases of accidental TCl exposure resulting in lung injury that may vary from a relatively mild and reversible interstitial lung disease to a severe form of bronchiolitis obliterans causing, after a latent period, an acute/chronic respiratory failure as well as other complications (spontaneous pneumothorax and bronchopleural fistula), previously unreported in TCl fume inhalation.

摘要

亚硫酰氯(TCl)用于制造锂电池,与水接触时会产生二氧化硫和氯化氢烟雾。我们报告了两例TCl意外暴露导致肺损伤的病例,损伤程度可能从相对轻微且可逆的间质性肺病到严重的闭塞性细支气管炎不等,后者在一段潜伏期后会导致急性/慢性呼吸衰竭以及其他并发症(自发性气胸和支气管胸膜瘘),此前未见TCl烟雾吸入导致这些并发症的报道。

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