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锌结合:人乳与牛乳的差异。

Zinc binding: a difference between human and bovine milk.

作者信息

Eckhert C D, Sloan M V, Duncan J R, Hurley L S

出版信息

Science. 1977 Feb 25;195(4280):789-90. doi: 10.1126/science.836589.

DOI:10.1126/science.836589
PMID:836589
Abstract

Gel chromatography indicated that most of the zinc in cow's milk was associated with high-molecular-weight fractions, whereas zinc in human milk was associated with low-molecular-weight fractions. A species difference in zinc-binding ligands may explain why symptoms of the genetic disorder of zinc metabolism, acrodermatitis enteropathica, can be alleviated by feeding human but not cow's milk.

摘要

凝胶色谱分析表明,牛奶中的大部分锌与高分子量组分相关,而人乳中的锌与低分子量组分相关。锌结合配体的物种差异可能解释了为什么锌代谢遗传疾病——肠病性肢端皮炎的症状可以通过喂食人乳而非牛奶来缓解。

相似文献

1
Zinc binding: a difference between human and bovine milk.锌结合:人乳与牛乳的差异。
Science. 1977 Feb 25;195(4280):789-90. doi: 10.1126/science.836589.
2
Zinc-binding properties of bovine and human milk in vitro: influence of changes in zinc content.牛和人乳在体外的锌结合特性:锌含量变化的影响
Am J Clin Nutr. 1980 May;33(5):1083-7. doi: 10.1093/ajcn/33.5.1083.
3
Zinc absorption from human milk, cow's milk, and infant formulas.人乳、牛乳和婴儿配方奶粉中的锌吸收情况。
Am J Dis Child. 1983 Aug;137(8):726-9. doi: 10.1001/archpedi.1983.02140340010002.
4
Bioavailability of zinc and its binding to casein in milks and formulas.锌在牛奶和配方奶中的生物利用度及其与酪蛋白的结合情况。
J Trace Elem Med Biol. 2000 Oct;14(3):146-53. doi: 10.1016/S0946-672X(00)80003-6.
5
Intestinal absorption of zinc: a role for a zinc-binding ligand in milk.锌的肠道吸收:牛奶中一种锌结合配体的作用。
Am J Physiol. 1978 Nov;235(5):E556-9. doi: 10.1152/ajpendo.1978.235.5.E556.
6
Zinc binding in cow's milk and human milk.牛奶和母乳中的锌结合
Biochem J. 1983 Feb 1;209(2):505-12. doi: 10.1042/bj2090505.
7
Digestion of the zinc in human milk, cow's milk and a commercial babyfood: some implications for human infant nutrition.人乳、牛乳及一种商业婴儿食品中锌的消化:对人类婴儿营养的一些启示。
Br J Nutr. 1986 Mar;55(2):209-17. doi: 10.1079/bjn19860027.
8
Isolation of a low molecular weight zinc binding ligand from human milk.从人乳中分离出一种低分子量锌结合配体。
J Inorg Biochem. 1980 Jan;12(1):71-8. doi: 10.1016/s0162-0134(00)80044-6.
9
Acrodermatitis enteropathica, zinc and human milk.肠病性肢端皮炎、锌与母乳。
Nutr Rev. 1978 Aug;36(8):241-2. doi: 10.1111/j.1753-4887.1978.tb07382.x.
10
Identification of copper- and zinc-binding ligands in human and bovine milk.
J Nutr. 1984 May;114(5):869-79. doi: 10.1093/jn/114.5.869.

引用本文的文献

1
A case of acrodermatitis enteropathica mimicking mutilating palmoplantar keratoderma.一例酷似致残性掌跖角化病的肠病性肢端皮炎病例。
Indian J Dermatol. 2022 May-Jun;67(3):314. doi: 10.4103/ijd.IJD_112_17.
2
When Is a Rare Disease Not so Rare? Implications for Medical Nutrition Therapy.罕见病何时不再罕见?对医学营养治疗的影响。
Integr Med (Encinitas). 2016 Mar;15(1):14-6.
3
Zinc: health effects and research priorities for the 1990s.锌:20世纪90年代的健康影响及研究重点
Environ Health Perspect. 1994 Jun;102 Suppl 2(Suppl 2):5-46. doi: 10.1289/ehp.941025.
4
Zinc-dependent chemotactic defect in an infant with acrodermatitis.一名患有肢端皮炎的婴儿存在锌依赖性趋化缺陷。
Arch Dis Child. 1980 Dec;55(12):966-8. doi: 10.1136/adc.55.12.966.
5
Drug excretion in human breast milk: principles, pharmacokinetics and projected consequences.药物在人乳中的排泄:原理、药代动力学及预期后果。
Clin Pharmacokinet. 1980 Jan-Feb;5(1):1-66. doi: 10.2165/00003088-198005010-00001.
6
Zinc binding in cow's milk and human milk.牛奶和母乳中的锌结合
Biochem J. 1983 Feb 1;209(2):505-12. doi: 10.1042/bj2090505.
7
[Effect of different concentrations of various zinc complexes (picolinate, citrate, 8-hydroxyquinolate) in comparison with sulfate on zinc supply status in rats].[不同浓度的各种锌配合物(吡啶甲酸盐、柠檬酸盐、8-羟基喹啉盐)与硫酸盐相比对大鼠锌供应状况的影响]
Z Ernahrungswiss. 1983 Jan;22(1):34-44. doi: 10.1007/BF02020783.
8
Effect of proteins on availability of zinc. I. Gastrointestinal transit time of casein and whey protein and zinc absorption in weaned rats.
Z Ernahrungswiss. 1985 Dec;24(4):245-55. doi: 10.1007/BF02023670.
9
Biochemistry of human milk in early lactation.初乳期人乳的生物化学
Z Ernahrungswiss. 1986 Jun;25(2):77-90. doi: 10.1007/BF02020737.
10
Serum zinc concentrations in exclusively breast-fed infants and in infants fed an adapted formula.纯母乳喂养婴儿和食用配方奶的婴儿的血清锌浓度。
Eur J Pediatr. 1986 Apr;144(6):598-600. doi: 10.1007/BF00496048.