Pley H W, Lindes D S, DeLuca-Flaherty C, McKay D B
Beckman Laboratories for Structural Biology, Department of Cell Biology, Stanford University School of Medicine, California 94305.
J Biol Chem. 1993 Sep 15;268(26):19656-8.
Hammerhead ribozyme-inhibitor complexes consisting of an RNA "enzyme" strand and a DNA "inhibitor" strand have been crystallized in four different crystal forms. The crystal form that is most attractive for structure determination diffracts to approximately 3.2 A resolution; it is trigonal, space group P3(1)21 or enantiomorph, a = 92.5 A, c = 185.0 A.
由一条RNA“酶”链和一条DNA“抑制剂”链组成的锤头状核酶-抑制剂复合物已以四种不同的晶体形式结晶。对结构测定最具吸引力的晶体形式衍射分辨率约为3.2埃;它是三方晶系,空间群P3(1)21或对映体,a = 92.5埃,c = 185.0埃。