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[测量阻抗以评估人体肝脏移植前的缺血损伤]

[Measuring impedance for evaluating ischemia damage to the human liver in preparation for transplantation].

作者信息

Erhard J, Lange R, Gersing E, Scherer R, Gebhard M M, Sanchez P, Bretschneider H J, Eigler F W

机构信息

Abteilung für Allgemeine Chirurgie, Universitätsklinikum Essen.

出版信息

Langenbecks Arch Chir. 1993;378(4):233-8. doi: 10.1007/BF00184365.

Abstract

In 22 human donor livers the measurement of the non-invasive bioelectrical impedance was performed prospectively to evaluate the degree of tissue damage sustained during cold ischemia. The results of the measurement were correlated with liver function, the method of organ preservation and the period of ischemia. The impedance was measured in vivo as 620 ohm (at 192 Hz), the phase angle as -7.4 degrees (at 5 kHz). The results were compared with the data obtained from 72 patients who underwent elective laparotomies. The 22 donor livers were studied further during ischemia. The method was found to be a reliable way of detecting severe damage to the hepatocytes during the cold ischemia.

摘要

对22个来自人类供体的肝脏进行前瞻性非侵入性生物电阻抗测量,以评估冷缺血期间组织损伤的程度。测量结果与肝功能、器官保存方法和缺血时间相关。体内测量的阻抗为620欧姆(192赫兹时),相位角为-7.4度(5千赫兹时)。将结果与72例行择期剖腹手术患者的数据进行比较。对22个供体肝脏在缺血期间进行了进一步研究。该方法被发现是检测冷缺血期间肝细胞严重损伤的可靠方法。

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