Palagiano A, Pace M C
I Facoltà di Medicina e Chirurgia, I Clinica Ostetrica e Ginecologica, II Università degli Studi di Napoli.
Minerva Pediatr. 1993 May;45(5):203-7.
The diagnosis of fetal tachyarrhythmia during a routine ultrasound scan imposes a continuous monitoring of fetal heart function through ECG and M-mode echocardiography. Since fetal dysrhythmia can lead to non-immune hydrops or to fetal death a correct diagnosis and an adequate intrauterine therapy are fundamentally important. The authors report the results obtained through a transplacental therapy with digoxin or with digoxin-verapamil in 8 cases with supraventricular tachyarrhythmia. Digoxin was very successful for conversion in sinus rhythm in 4 cases. The combination digoxin-verapamil led to the conversion in only one case resistant to the digoxin therapy.
在常规超声扫描期间诊断出胎儿心律失常后，需通过心电图和M型超声心动图对胎儿心脏功能进行持续监测。由于胎儿心律失常可能导致非免疫性水肿或胎儿死亡，因此正确的诊断和适当的宫内治疗至关重要。作者报告了8例室上性心律失常病例经胎盘使用地高辛或地高辛-维拉帕米治疗的结果。地高辛使4例成功转为窦性心律。地高辛-维拉帕米联合用药仅使1例对地高辛治疗耐药的病例转为窦性心律。
