Hajdú J, Szabó I, Német J
Semmelweis Orvostudományi Egyetem I. Szülészeti és Nógyógyászati Klinika, Budapest.
Orv Hetil. 1996 Oct 6;137(40):2209-11.
The supraventricular tachycardia is a life threatening state in the intrauterine life. It can cause non-immune hydrops fetalis, intrauterine death or complications during the delivery. The unexplained tachycardia can cause fetal distress and premature delivery. Usually the digoxin is the first drug of choice for transplacental cardioversion. If digitalisation does not achieve cardioversion, the second line antiarrhythmic drugs should be instituted. Amiodarone has been suggested as a therapeutic alternative after failure of digoxin-verapamil combination. We give a drug in standard therapeutic doses for four-five days and after it we determine whether it is effective or not. We should determine the newer therapy or termination of pregnancy. The transplacental administration of amiodarone may be dangerous because of fetal cretinism. Our case is the first in Hungary-in our best knowledge- and we suggest the amiodarone for transplacental therapy.
室上性心动过速在子宫内是一种危及生命的状态。它可导致非免疫性胎儿水肿、宫内死亡或分娩期间的并发症。不明原因的心动过速可引起胎儿窘迫和早产。通常地高辛是经胎盘心脏复律的首选药物。如果洋地黄化不能实现心脏复律，则应使用二线抗心律失常药物。在使用地高辛 - 维拉帕米联合治疗失败后，胺碘酮已被建议作为一种治疗选择。我们以标准治疗剂量给药四至五天，之后确定其是否有效。我们应确定更新的治疗方法或终止妊娠。由于胎儿先天性甲状腺功能减退，经胎盘给予胺碘酮可能是危险的。据我们所知，我们的病例是匈牙利首例，我们建议使用胺碘酮进行经胎盘治疗。
