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局部使用糖皮质激素所致库欣综合征

Cushing's syndrome from topical glucocorticoids.

作者信息

Teelucksingh S, Bahall M, Coomansingh D, Suite M, Bartholomew C

机构信息

Department of Medicine, Port-of-Spain General Hospital, Trinidad.

出版信息

West Indian Med J. 1993 Jun;42(2):77-8.

PMID:8367969
Abstract

A case of Cushing's syndrome is described in a woman who self-treated psoriasis with a variety of potent topical glucocorticoids over 15 years. She was successfully weaned off corticosteroids and was treated with alternative anti-psoriatic drugs. The disappearance, nine months later, of most features of Cushing's syndrome, and the normal suppression of cortisol in response to dexamethasone, excluded endogenous hypercorticolism. The apparent widespread availability across the counter of potent corticosteroids is a cause for concern.

摘要

本文描述了一例库欣综合征患者,该女性15年来一直自行使用多种强效外用糖皮质激素治疗银屑病。她成功停用了皮质类固醇,并接受了其他抗银屑病药物治疗。九个月后,库欣综合征的大多数症状消失,且地塞米松刺激试验显示皮质醇正常抑制,排除了内源性皮质醇增多症。强效皮质类固醇在柜台似乎广泛可得,这令人担忧。

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