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癌胚抗原(CEA)在血尿中的临床诊断价值。

The clinical diagnostic value of the carcinoembryonic antigen (CEA) in haematuria.

作者信息

Turner A G, Carter S, Higgins E, Glashan R W, Neville A M

出版信息

Br J Urol. 1977 Feb;49(1):61-6. doi: 10.1111/j.1464-410x.1977.tb04525.x.

DOI:10.1111/j.1464-410x.1977.tb04525.x
PMID:837050
Abstract

Plasma and urinary CEA levels in patients presenting with haematuria have been studied to assess whether they facilitate the differentiation between benign and malignant urothelial conditions. Plasma CEA is of no diagnostic value although, if raised, it may suggest an invasive tumour. Urinary CEA levels are only of value in the absence of urinary infection; even then, only 37% of the cases with overt urothelial tumours had raised titres. A knowledge of the urinary CEA level, therefore, would seem to contribute little to the diagnosis of patients presenting with haematuria and all patients must still be investigated by the conventional techniques of urinary bacteriology, cytology, intravenous pyelography and cystourethroscopy.

摘要

对出现血尿的患者的血浆和尿液癌胚抗原(CEA)水平进行了研究,以评估它们是否有助于区分良性和恶性尿路上皮疾病。血浆CEA没有诊断价值,不过,如果其水平升高,可能提示存在浸润性肿瘤。尿CEA水平仅在无泌尿系统感染时才有价值;即便如此,在明显的尿路上皮肿瘤病例中,也只有37%的病例其滴度升高。因此,尿CEA水平的信息似乎对血尿患者的诊断帮助不大,所有患者仍必须通过泌尿系统细菌学、细胞学、静脉肾盂造影和膀胱尿道镜检查等传统技术进行检查。

相似文献

1
The clinical diagnostic value of the carcinoembryonic antigen (CEA) in haematuria.癌胚抗原(CEA)在血尿中的临床诊断价值。
Br J Urol. 1977 Feb;49(1):61-6. doi: 10.1111/j.1464-410x.1977.tb04525.x.
2
The clinical value of plasma and urinary carcinoembryonic antigen (CEA) assays in patients with haematuria and urothelial carcinoma.血浆和尿癌胚抗原(CEA)检测在血尿和尿路上皮癌患者中的临床价值
Eur Urol. 1980;6(6):344-6. doi: 10.1159/000473369.
3
Urinary carcinoembryonic antigen (CEA)-like molecules and urothelial malignancy: a clinical appraisal.尿癌胚抗原(CEA)样分子与尿路上皮恶性肿瘤:一项临床评估
Br J Cancer. 1975 Feb;31(2):135-42. doi: 10.1038/bjc.1975.18.
4
The carcinoembryonic antigen test in urologic cancer.泌尿系统癌症中的癌胚抗原检测
Natl Cancer Inst Monogr. 1978 Dec(49):225-9.
5
Carcinoembryonic antigen in effusions. A diagnostic adjunct to cytology.体腔积液中的癌胚抗原。细胞学诊断的辅助手段。
Acta Cytol. 1987 Mar-Apr;31(2):113-8.
6
[Plasma and urinary CEA-assay in patients with urological tumours (author's transl)].
Urologe A. 1976 Nov;15(6):300-3.
7
Diagnostic value of urine cytology and urine carcinoembryonic antigen (CEA) level in the distinction between bladder cancer and urinary tract infection.尿细胞学检查及尿癌胚抗原(CEA)水平在鉴别膀胱癌与尿路感染中的诊断价值。
Int J Occup Med Environ Health. 1995;8(2):103-8.
8
The CEA test in urologic cancer: an evaluation and a review.泌尿外科癌症中的癌胚抗原检测:一项评估与综述。
Oncology. 1975;32(3-4):158-68. doi: 10.1159/000225062.
9
[CEA determination in urogenital tract neoplasms].[泌尿生殖道肿瘤中癌胚抗原的测定]
Med Lab (Stuttg). 1976 Sep;29(9):193-8.
10
The clinical utility of plasma and urinary carcinoembryonic antigen in patients with genitourinary disease.血浆和尿癌胚抗原在泌尿生殖系统疾病患者中的临床应用价值。
J Urol. 1977 May;117(5):635-7. doi: 10.1016/s0022-5347(17)58567-5.

引用本文的文献

1
Urine carcinoembryonic antigen levels are more useful than serum levels for early detection of Bilharzial and non-Bilharzial urinary bladder carcinoma: observations of 43 Egyptian cases.尿癌胚抗原水平在早期检测埃及血吸虫性和非埃及血吸虫性膀胱癌方面比血清水平更有用:43例埃及病例的观察结果
World J Surg Oncol. 2007 Jan 15;5:4. doi: 10.1186/1477-7819-5-4.
2
The haematuria clinic.血尿诊所
BMJ. 1994 Feb 5;308(6925):356. doi: 10.1136/bmj.308.6925.356.
3
Immunohistochemical demonstration of tumor-associated antigens with the aid of monoclonal and polyclonal antisera in carcinoma of the bladder.
Urol Res. 1985;13(2):55-9. doi: 10.1007/BF00261566.