Peters M, Gottschalk D, Boit R, Pohle H D, Ruf B
II. Department of Internal Medicine, Rudolf Virchow University Hospital, Freie Universität, Berlin, Germany.
J Infect. 1993 Jul;27(1):57-62. doi: 10.1016/0163-4453(93)93768-y.
The acquired immunodeficiency syndrome (AIDS) appears to alter the course of syphilis and particularly neurosyphilis. We report the case of an HIV-positive patient with two CNS lesions due to vascular complications of neurosyphilis of the meningovascular type, 18 months after he had developed a penile chancre. On admission, CT scans were inconsistent with cerebral toxoplasmosis or CNS lymphoma. At necropsy, histopathological examination showed typical Heubner's endarteritis of the basilar and posterior cerebral arteries. In AIDS patients, superadded meningovascular syphilis must be suspected, especially when CT scanning reveals the presence of multi-focal, low density lesions with the particular characteristics of infarction.
获得性免疫缺陷综合征（艾滋病）似乎会改变梅毒尤其是神经梅毒的病程。我们报告一例HIV阳性患者，在出现阴茎硬下疳18个月后，因脑膜血管型神经梅毒的血管并发症出现两处中枢神经系统病变。入院时，CT扫描结果与脑弓形虫病或中枢神经系统淋巴瘤不符。尸检时，组织病理学检查显示基底动脉和大脑后动脉存在典型的霍伊布纳动脉内膜炎。在艾滋病患者中，必须怀疑合并脑膜血管梅毒，尤其是当CT扫描显示存在具有梗死特征的多灶性低密度病变时。
