Beevers D G, Morton J J, Nelson C S, Padfield P L, Titterington M, Tree M
Br Med J. 1977 Feb 12;1(6058):415. doi: 10.1136/bmj.1.6058.415.
Plasma concentrations of angiotensin II (PAC) were measured in a group of 146 hypertensive patients (diastolic pressure greater than 105 mm Hg) who had no apparent underlying cause for their condition and 113 randomly selected normotensive controls (diastolic pressure less than 90 mm Hg). There was no evidence of bimodality in the frequency distribution curves for plasma angiotensin II concentrations among the hypertensive patients. It was concluded that hypertension associated with low angiotensin II concentration and by implication "low-renin" hypertension is not a condition separate from essential hypertension.
在一组146例高血压患者(舒张压大于105 mmHg)中测量了血浆血管紧张素II浓度(PAC),这些患者没有明显的潜在病因,同时选取了113名随机选择的血压正常对照者(舒张压小于90 mmHg)。在高血压患者中,血浆血管紧张素II浓度的频率分布曲线没有双峰分布的证据。得出的结论是,与低血管紧张素II浓度相关的高血压以及由此推断的“低肾素”高血压并非与原发性高血压不同的疾病。