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[红细胞指数在婴儿铁储存研究中的应用价值]

[Usefulness of erythrocyte indices in the study of iron storage in infants].

作者信息

Baptista-González H A, Peñuela-Olaya M A, Negrete-Valenzuela F, Ramírez-Vela J

机构信息

Instituto Nacional de Perinatología, México, D.F., México.

出版信息

Bol Med Hosp Infant Mex. 1993 Sep;50(9):639-44.

PMID:8373544
Abstract

For establishment correlation between erythrocyte indices and serum ferritin (SF), to identify infants at eighth months of age, with iron normal corporal stores, were studied 112 infants; 40 cases had severe deficient iron stores (SF < 12 ng/mL), 17 cases with "moderate" deficient iron stores (SF 12-20 ng/mL) and 55 infants with normal iron stores. The mean corpuscular hemoglobin (MCH) was altered in the 40.1%, the mean corpuscular volume (MCV) 29.5% and hemoglobin (Hb) 6.2%. In severe deficient iron stores, the MCH, with abnormal values had minor specificity (0.62), that MCV (0.88). With a SF < 20 ng/mL, specificity of the MCV was 0.92. Simultaneous alteration on MCH and MCV had similar specificity (0.92) and predictive positive values. With abnormal values of CMH + MCV or MCV alone, were established high probability for identify infants with normal iron stores.

摘要

为了建立红细胞指数与血清铁蛋白(SF)之间的相关性,对112名8个月大、体内铁储备正常的婴儿进行了研究;40例铁储备严重不足(SF<12 ng/mL),17例铁储备“中度”不足(SF 12 - 20 ng/mL),55例铁储备正常。40.1%的平均红细胞血红蛋白(MCH)、29.5%的平均红细胞体积(MCV)和6.2%的血红蛋白(Hb)发生改变。在铁储备严重不足时,MCH异常值的特异性较低(0.62),MCV的特异性为(0.88)。当SF<20 ng/mL时,MCV的特异性为0.92。MCH和MCV同时改变具有相似的特异性(0.92)和预测阳性值。CMH + MCV或单独MCV异常时,识别铁储备正常婴儿的概率较高。

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