Legler U F, Assia E I, Apple D J
Department of Ophthalmology, Medical University of South Carolina, Charleston.
Ophthalmologe. 1993 Aug;90(4):339-42.
The effect of posterior chamber intraocular lenses (PC-IOLs) on the capsular bag was investigated in human cadaver eyes. Short-term changes were observed with different PC-IOLs directly after experimental implantation. Long-term results were obtained from postmortem eyes with PC-IOLs. Mean implant duration was 2.5 years. The average diameter of the capsular bag in the loop axis was 11.0 mm for 12.0 mm IOLs and 11.5 mm for 13.5-14.0 mm IOLs in the short-term study. Longer loops caused more ovaling of the bag with stress lines on the posterior capsule. The average diameter of the capsular bag in the long term study was 10.6 mm. Secondary processes such as capsular fibrosis and lens epithelial cell proliferation caused the capsular bag to shrink and thus to assume a more circular configuration. The area of contact between the IOL loops and the capsular equator was significantly lower in eyes with radial tears and IOLs with J-loop design when compared to C-loops. The maximal capsular diameter in both the long-term and short-term observations never exceeded 12.0 mm. The results of our study suggest that a 12.0 mm total diameter IOL is sufficient for stable fixation, provided that capsular bag implantation can be assured.
在人类尸体眼中研究了后房型人工晶状体（PC-IOL）对囊袋的影响。在实验植入后，直接观察不同PC-IOL的短期变化。从植入PC-IOL的尸眼中获得长期结果。平均植入时间为2.5年。在短期研究中，对于12.0 mm的人工晶状体，囊袋在襻轴方向的平均直径为11.0 mm，对于13.5 - 14.0 mm的人工晶状体，囊袋平均直径为11.5 mm。较长的襻会使囊袋更呈椭圆形，后囊膜出现应力线。长期研究中囊袋的平均直径为10.6 mm。诸如囊膜纤维化和晶状体上皮细胞增殖等继发性过程导致囊袋收缩，从而呈现出更圆形的形态。与C形襻相比，在有放射状撕裂的眼中以及采用J形襻设计的人工晶状体中，人工晶状体襻与囊袋赤道之间的接触面积显著更低。在长期和短期观察中，囊袋的最大直径从未超过12.0 mm。我们的研究结果表明，只要能确保囊袋内植入，总直径为12.0 mm的人工晶状体足以实现稳定固定。
