Woodsmall R M, Benson D A
National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland 20894.
Bull Med Libr Assoc. 1993 Jul;81(3):282-4.
The National Center for Biotechnology Information (NCBI), part of the National Library of Medicine, was established in 1988 to perform basic research in the field of computational molecular biology as well as build and distribute molecular biology databases. The basic research has led to new algorithms and analysis tools for interpreting genomic data and has been instrumental in the discovery of human disease genes for neurofibromatosis and Kallmann syndrome. The principal database responsibility is the National Institutes of Health (NIH) genetic sequence database, GenBank. NCBI, in collaboration with international partners, builds, distributes, and provides online and CD-ROM access to over 112,000 DNA sequences. Another major program is the integration of multiple sequences databases and related bibliographic information and the development of network-based retrieval systems for Internet access.
美国国立医学图书馆下属的国立生物技术信息中心(NCBI)成立于1988年,旨在开展计算分子生物学领域的基础研究,以及构建和分发分子生物学数据库。基础研究催生了用于解读基因组数据的新算法和分析工具,并在发现神经纤维瘤病和卡尔曼综合征的人类疾病基因方面发挥了重要作用。主要的数据库职责是维护美国国立卫生研究院(NIH)的遗传序列数据库GenBank。NCBI与国际合作伙伴合作,构建、分发并提供对超过112,000个DNA序列的在线和光盘访问。另一个主要项目是整合多个序列数据库及相关文献信息,并开发基于网络的检索系统以供互联网访问。