Convenient syntheses of oligonucleotides linked to 5-deazaflavin coenzyme models at 3'-end. Incorporation of 5-deazaflavin to controlled pore glass (CPG) support.
作者信息
Nakamura Y, Akiyama T, Bessho K, Yoneda F
机构信息
Faculty of Pharmaceutical Sciences, Kyoto University, Japan.
出版信息
Chem Pharm Bull (Tokyo). 1993 Jul;41(7):1315-7. doi: 10.1248/cpb.41.1315.
PMID:8375000
Abstract
Using CPG support linked with 5-deazaflavin, the 5-deazaflavin modified oligodeoxynucleotides at 3'-end(ODN-dF1) were synthesized. The thermal stability of the duplex of ODN-dF1 with its complement was higher than that of oligonucleotide linked to 5-deazaflavin at 5'-end internucleotide linkage.
摘要
Zotero 插件