Jacobs E, Nowakowski M, Colman N
Department of Pathology, Mount Sinai School of Medicine, Mount Sinai Hospital, New York, NY 10029.
Clin Chem. 1993 Sep;39(9):1890-3.
We evaluated a new analyzer designed for point-of-care testing of blood gases, sodium, potassium, ionized calcium, and hematocrit. The Gem Premier (Mallinckrodt) system has two components: the analyzer and a disposable cartridge. Analysis takes place in the cartridge, which contains the electrochemical sensors, the calibrants, the reagents, the sampling stylus, and the waste container. The system was evaluated for imprecision and accuracy. With aqueous control materials, total imprecision (CV) was: pH, 0.10-0.18%; PCO2, 3.16-5.78%; PO2, 2.92-4.85%; sodium, 0.82-1.44%; potassium, 1.35-1.48%; ionized calcium, 0.75-1.45%; and hematocrit, 1.13-1.83%. Accuracy of the system was assessed by split-sample comparison with the Radiometer ABL 330 blood gas analyzer for pH and blood gases, the Nova Stat Profile 5 for whole-blood electrolyte and hematocrit analysis, and the IL Phoenix for plasma electrolyte analysis. After outlier correction, regression statistics were excellent for all analytes except sodium, which demonstrated Sy[x values between 1.80 and 2.30 mmol/L and 0.85 < or = r < 0.90.
我们评估了一款专为即时检测血气、钠、钾、离子钙和血细胞比容而设计的新型分析仪。Gem Premier（马林克罗德特公司）系统有两个组件：分析仪和一次性试剂盒。分析在试剂盒中进行，试剂盒包含电化学传感器、校准物、试剂、采样探针和废物容器。对该系统的不精密度和准确性进行了评估。使用水性对照材料时，总不精密度（CV）为：pH值，0.10 - 0.18%；二氧化碳分压，3.16 - 5.78%；氧分压，2.92 - 4.85%；钠，0.82 - 1.44%；钾，1.35 - 1.48%；离子钙，0.75 - 1.45%；血细胞比容，1.13 - 1.83%。通过与Radiometer ABL 330血气分析仪进行pH值和血气的分样比较、与Nova Stat Profile 5进行全血电解质和血细胞比容分析、以及与IL Phoenix进行血浆电解质分析，评估了该系统的准确性。经过异常值校正后，除钠外，所有分析物的回归统计结果都非常出色，钠的Sy[x值在1.80至2.30 mmol/L之间，0.85≤r＜0.90。
