生长激素-催乳素基因家族中的核苷酸替换模式：基因复制进化的一个范例。
Pattern of nucleotide substitutions in growth hormone-prolactin gene family: a paradigm for evolution by gene duplication.
作者信息
Ohta T
机构信息
National Institute of Genetics, Mishima, Japan.
出版信息
Genetics. 1993 Aug;134(4):1271-6. doi: 10.1093/genetics/134.4.1271.
Abstract
The growth hormone-prolactin gene family in mammals is an interesting example of evolution by gene duplication. Divergence among members of duplicated gene families and among species was examined by using reported gene sequences of growth hormone, prolactin and their receptors. Sequence divergence among species was found to show a general tendency in which a generation-time effect is pronounced for synonymous substitutions but not so for nonsynonymous substitutions. Divergence among duplicated genes is characterized by the relatively high rate of nonsynonymous substitutions, i.e., the rate is close to that of synonymous ones. In view of the stage- and tissue-specific expression of duplicated genes, some of the amino acid substitutions among duplicated genes is likely to be caused by positive Darwinian selection.
摘要
哺乳动物中的生长激素 - 催乳素基因家族是基因复制进化的一个有趣例子。通过使用已报道的生长激素、催乳素及其受体的基因序列，研究了复制基因家族成员之间以及物种之间的差异。发现物种间的序列差异呈现出一种普遍趋势，即同义替换的世代时间效应明显，而异义替换则不然。复制基因之间的差异表现为相对较高的非同义替换率，即该速率接近同义替换率。鉴于复制基因的阶段和组织特异性表达，复制基因之间的一些氨基酸替换可能是由正向达尔文选择引起的。
相似文献
1
Pattern of nucleotide substitutions in growth hormone-prolactin gene family: a paradigm for evolution by gene duplication.生长激素-催乳素基因家族中的核苷酸替换模式：基因复制进化的一个范例。
Genetics. 1993 Aug;134(4):1271-6. doi: 10.1093/genetics/134.4.1271.
2
Evolution of the growth hormone, prolactin, prolactin 2 and somatolactin family.生长激素、催乳素、催乳素2和生长抑素家族的进化。
Gen Comp Endocrinol. 2018 Aug 1;264:94-112. doi: 10.1016/j.ygcen.2018.01.007. Epub 2018 Jan 12.
3
Gene structure of chum salmon somatolactin, a presumed pituitary hormone of the growth hormone/prolactin family.大麻哈鱼生长抑素的基因结构，生长抑素是一种推测为生长激素/催乳素家族的垂体激素。
Mol Endocrinol. 1991 Jun;5(6):778-86. doi: 10.1210/mend-5-6-778.
4
Further examples of evolution by gene duplication revealed through DNA sequence comparisons.通过DNA序列比较揭示的基因复制导致进化的更多例子。
Genetics. 1994 Dec;138(4):1331-7. doi: 10.1093/genetics/138.4.1331.
5
6
Molecular evolution of prolactin in primates.灵长类动物中催乳素的分子进化
J Mol Evol. 2005 May;60(5):606-14. doi: 10.1007/s00239-004-0239-9.
7
Origin and evolution of gene for prolactin-induced protein.催乳素诱导蛋白基因的起源与进化。
Gene. 2006 Nov 15;383:64-70. doi: 10.1016/j.gene.2006.07.014. Epub 2006 Jul 28.
8
The ghost of selection past: rates of evolution and functional divergence of anciently duplicated genes.过去选择的印记：古老重复基因的进化速率与功能分化
J Mol Evol. 2001 Oct-Nov;53(4-5):436-46. doi: 10.1007/s002390010233.
9
Variable evolutionary rates in the molecular evolution of mammalian growth hormones.哺乳动物生长激素分子进化中的可变进化速率。
J Mol Evol. 1994 Jun;38(6):619-27. doi: 10.1007/BF00175882.
引用本文的文献
1
β2-microglobulin gene duplication in cetartiodactyla remains intact only in pigs and possibly confers selective advantage to the species.偶蹄目动物中的β2微球蛋白基因重复仅在猪中保持完整，可能赋予该物种选择性优势。
PLoS One. 2017 Aug 16;12(8):e0182322. doi: 10.1371/journal.pone.0182322. eCollection 2017.
2
Molecular evolution of UCP1 and the evolutionary history of mammalian non-shivering thermogenesis.解偶联蛋白1的分子进化与哺乳动物非颤抖性产热的进化史
BMC Evol Biol. 2009 Jan 7;9:4. doi: 10.1186/1471-2148-9-4.
3
Complex signatures of locus-specific selective pressures and gene conversion on Human Growth Hormone/Chorionic Somatomammotropin genes.人类生长激素/绒毛膜促生长催乳素基因位点特异性选择压力和基因转换的复杂特征
Hum Mutat. 2008 Oct;29(10):1181-93. doi: 10.1002/humu.20767.
4
Evolutionary insights into the unique electromotility motor of mammalian outer hair cells.对哺乳动物外毛细胞独特电运动马达的进化见解。
Evol Dev. 2008 May-Jun;10(3):300-15. doi: 10.1111/j.1525-142X.2008.00239.x.
5
Whole-gene positive selection, elevated synonymous substitution rates, duplication, and indel evolution of the chloroplast clpP1 gene.叶绿体clpP1基因的全基因正向选择、同义替换率升高、基因重复及插入缺失进化
PLoS One. 2008 Jan 2;3(1):e1386. doi: 10.1371/journal.pone.0001386.
6
Molecular evolution of the ependymin protein family: a necessary update.室管膜蛋白家族的分子进化：一次必要的更新
BMC Evol Biol. 2007 Feb 15;7:23. doi: 10.1186/1471-2148-7-23.
7
Evolution of growth hormone in primates: the GH gene clusters of the New World monkeys marmoset (Callithrix jacchus) and white-fronted capuchin (Cebus albifrons).灵长类动物生长激素的进化：新世界猴狨猴（绢毛猴）和白额卷尾猴的生长激素基因簇
J Mol Evol. 2006 Nov;63(5):591-601. doi: 10.1007/s00239-006-0039-5. Epub 2006 Sep 26.
8
Cloning, functional identification and sequence analysis of flavonoid 3'-hydroxylase and flavonoid 3',5'-hydroxylase cDNAs reveals independent evolution of flavonoid 3',5'-hydroxylase in the Asteraceae family.黄酮类3'-羟化酶和黄酮类3',5'-羟化酶cDNA的克隆、功能鉴定及序列分析揭示了菊科中黄酮类3',5'-羟化酶的独立进化。
Plant Mol Biol. 2006 Jun;61(3):365-81. doi: 10.1007/s11103-006-0012-0.
9
Gene conversion and functional divergence in the beta-globin gene family.β-珠蛋白基因家族中的基因转换与功能分化
J Mol Evol. 2004 Aug;59(2):177-89. doi: 10.1007/s00239-004-2612-0.
10
Episodic molecular evolution of pituitary growth hormone in Cetartiodactyla.鲸偶蹄目垂体生长激素的间歇性分子进化
J Mol Evol. 2004 Jun;58(6):743-53. doi: 10.1007/s00239-004-2595-x.
本文引用的文献
1
Construction and characterization of a cDNA clone containing a portion of the bovine prolactin sequence.包含部分牛催乳素序列的cDNA克隆的构建与鉴定
Nucleic Acids Res. 1980 Apr 11;8(7):1561-73. doi: 10.1093/nar/8.7.1561.
2
Cloning of DNA complementary to bovine prolactin mRNA.与牛催乳素信使核糖核酸互补的DNA的克隆
Endocrinology. 1980 Sep;107(3):851-3. doi: 10.1210/endo-107-3-851.
3
Structure of cloned DNA complementary to rat prolactin messenger RNA.与大鼠催乳素信使核糖核酸互补的克隆DNA的结构
J Biol Chem. 1980 Jul 10;255(13):6502-10.
4
Primary structure and evolution of rat growth hormone gene.大鼠生长激素基因的一级结构与进化
Proc Natl Acad Sci U S A. 1981 Aug;78(8):4867-71. doi: 10.1073/pnas.78.8.4867.
5
Human prolactin. cDNA structural analysis and evolutionary comparisons.人催乳素。cDNA结构分析及进化比较。
J Biol Chem. 1981 Apr 25;256(8):4007-16.
6
On the stochastic model for estimation of mutational distance between homologous proteins.关于同源蛋白质间突变距离估计的随机模型。
J Mol Evol. 1972 Dec 29;2(1):87-90. doi: 10.1007/BF01653945.
7
Isolation and characterization of the porcine growth hormone gene.
Gene. 1987;55(2-3):339-44. doi: 10.1016/0378-1119(87)90294-0.
8
Molecular cloning of a prolactin-related mRNA expressed in bovine placenta.在牛胎盘中表达的一种催乳素相关信使核糖核酸的分子克隆
Proc Natl Acad Sci U S A. 1987 Aug;84(16):5650-4. doi: 10.1073/pnas.84.16.5650.
9
Simple methods for estimating the numbers of synonymous and nonsynonymous nucleotide substitutions.估计同义与非同义核苷酸替换数目的简单方法。
Mol Biol Evol. 1986 Sep;3(5):418-26. doi: 10.1093/oxfordjournals.molbev.a040410.
10
Nucleotide sequence of the growth hormone gene cDNA from goat Capra hircus L. (Tokara).来自山羊（卡普拉·希尔克斯，托卡拉品种）生长激素基因cDNA的核苷酸序列。
Nucleic Acids Res. 1988 Apr 25;16(8):3578. doi: 10.1093/nar/16.8.3578.
Zotero 插件