Suppr超能文献

肺动脉导管监测的临床应用

Clinical utilization of pulmonary artery catheter monitoring.

作者信息

Vender J S

机构信息

Northwestern University Medical School, Chicago, Illinois.

出版信息

Int Anesthesiol Clin. 1993 Summer;31(3):57-85. doi: 10.1097/00004311-199331030-00006.

Abstract

Since the introduction of PA catheter monitoring in 1970, the applications for it have dramatically broadened. PA catheters are used to obtain hemodynamic data for the assessment, monitoring, and therapeutic management of critically ill, high-risk surgical patients. Because of potential complications associated with PA catheter monitoring, numerous editorials and articles have questioned the procedure's risk-to-benefit ratio. These articles address the inadequacy of outcome data and suggest no demonstrated benefit from PA monitoring. Subgroups of patients have been identified, however, in whom PA monitoring data altered clinicians' assessment and management. In spite of a study by Rao and colleagues implying that PA catheter monitoring can decrease the mortality rate in critically ill patients, no scientific study has confirmed this impression. A more recent article evaluated the impact of PA catheter monitoring on mortality with emphasis on how the information is used. This prospective study noted a potential benefit from PA catheter monitoring in a protocol group, but the limited sample size and selection criteria prevent definitive conclusions. Unfortunately, many of the reported studies are retrospective, nonrandomized, unblinded, limited in scope or size, and founded on subjective end points. Careful evaluation of individual studies is mandatory to avoid overinterpretation of the conclusions. Understanding the limits of PA monitoring is needed for therapy to be successful. Problems may stem not from technology but from the knowledge and expectations of clinicians. "Human" complications from inadequate understanding of the physiological data is not uncommon. Measured pressures by themselves can be misleading; indeed use of absolute numbers rather than trends or relative changes in the values monitored can compromise clinical assessment. Overzealous acceptance and utilization of any quantitative measurement without sound clinical judgment is fraught with failure.

摘要

自1970年肺动脉导管监测引入以来,其应用范围已大幅拓宽。肺动脉导管用于获取血流动力学数据,以评估、监测和治疗危重症、高风险手术患者。由于肺动脉导管监测存在潜在并发症,众多社论和文章对该操作的风险效益比提出了质疑。这些文章指出结局数据不充分,并表明肺动脉监测未显示出明显益处。然而,已确定有部分患者亚组,肺动脉监测数据改变了临床医生的评估和管理。尽管饶及其同事的一项研究暗示肺动脉导管监测可降低危重症患者的死亡率,但尚无科学研究证实这一观点。最近的一篇文章评估了肺动脉导管监测对死亡率的影响,重点在于信息的使用方式。这项前瞻性研究指出在一个方案组中肺动脉导管监测有潜在益处,但样本量有限和选择标准限制了得出确定性结论。不幸的是,许多报道的研究是回顾性的、非随机的、非盲法的、范围或规模有限且基于主观终点。必须仔细评估个别研究,以避免对结论过度解读。要使治疗成功,需要了解肺动脉监测的局限性。问题可能并非源于技术,而是源于临床医生的知识和期望。因对生理数据理解不足导致的“人为”并发症并不罕见。测量的压力本身可能会产生误导;实际上,使用绝对值而非监测值的趋势或相对变化可能会影响临床评估。在没有合理临床判断的情况下过度热心地接受和使用任何定量测量都充满失败风险。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验