Vender J S
Northwestern University, Evanston, Illinois.
Crit Care Clin. 1988 Jul;4(3):455-77.
Since its introduction in 1970, the application for PA catheter monitoring has dramatically broadened. PA catheters provide the ability to obtain hemodynamic data for the assessment, monitoring, and therapeutic management of critically ill patients. Because of the potential complications associated with PA catheter monitoring, numerous editorials and articles have questioned the procedure's risk to benefit ratio. These articles address the insufficient availability of adequate outcome data or suggest no demonstrated benefit from PA monitoring. Subgroups of patients have been identified in whom the data obtained from PA monitoring altered the clinician's assessment and management. In spite of the study of Rao, which implies that PA catheters can improve mortality in critically ill patients, no scientific study of outcome has been able to confirm this impression. If an adequate understanding of the limitations of PA monitoring does not exist, appropriate selection and implementation of therapy cannot occur. The problem is not as much the technology, as it is the knowledge and expectations of the clinician. "Human" complications from inadequate understanding of the physiologic data are quite common. Reliance on the measured pressure is often misleading. The use of "absolute numbers" rather than trends or relative changes in the values monitored can compromise clinical assessment. Overzealous utilization and acceptance of any quantitative measurement without coordination with clinical judgment is fraught with failure.
自1970年肺动脉导管监测技术问世以来,其应用范围已大幅拓宽。肺动脉导管能够获取血流动力学数据,用于评估、监测和治疗重症患者。由于肺动脉导管监测存在潜在并发症,众多社论和文章对该操作的风险效益比提出质疑。这些文章指出,缺乏足够的有效结局数据,或者表明肺动脉监测未显示出明显益处。已确定部分患者亚组,从他们身上获得的肺动脉监测数据改变了临床医生的评估和治疗方案。尽管饶氏研究表明肺动脉导管可降低重症患者的死亡率,但尚无科学研究能证实这一观点。如果对肺动脉监测的局限性缺乏充分认识,就无法进行恰当的治疗选择和实施。问题并不在于技术本身,而在于临床医生的知识和期望。因对生理数据理解不足而导致的“人为”并发症十分常见。依赖测量压力往往具有误导性。使用“绝对数值”而非监测值的趋势或相对变化,可能会影响临床评估。在未与临床判断相结合的情况下,过度热衷于使用和接受任何定量测量,往往会导致失败。