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[Modification of ischemia and reperfusion damage of skeletal muscles with allopurinol: in vivo 31P MR spectroscopy of the posterior limb of the rat].

作者信息

Gürke L, Marx A, Erhard P, Sutter P M, Landmann J, Heberer M

机构信息

Department Chirurgie, Kantonsspital, Universität Basel.

出版信息

Helv Chir Acta. 1993 Jun;59(5-6):877-80.

PMID:8376157
Abstract

The effect of Allopurinol on energy metabolism (re-utilisation of hypoxanthine) was studied in a in vivo skeletal muscle ischemia rat model by 31-P-MR spectroscopy. Allopurinol-treatment showed no benefit to the kinetics of PCr/(Pi + PCr) and ATP/(Pi + PCr). The role of re-utilisation of hypoxanthine has to be further investigated.

摘要

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