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豚鼠中乳酸脱氢酶同工酶的个体发生活性及其与细胞结构的相互作用。

Ontogenic activities and interactions of the lactate dehydrogenase isozymes with cellular structure in the guinea pig.

作者信息

Murrell W, Crane D, Masters C

机构信息

Division of Science and Technology, Griffith University, Brisbane, Australia.

出版信息

Mech Ageing Dev. 1993 Jun;69(1-2):37-52. doi: 10.1016/0047-6374(93)90070-8.

DOI:10.1016/0047-6374(93)90070-8
PMID:8377529
Abstract

The LDH activities and isozyme distributions associated with soluble and particulate fractions of five major tissues have been followed during the development of the guinea pig. Evidence has been provided for an appreciable degree of interaction between LDH and cellular structure in all these tissues (liver, kidney, skeletal muscle, brain and heart) at all stages of development, but particularly in the early foetal stages. These data have been discussed in relation to the nature and extent of this binding and the correlations with the metabolic emphases in these tissue situations during development.

摘要

在豚鼠发育过程中,对五个主要组织的可溶性和颗粒部分相关的乳酸脱氢酶(LDH)活性及同工酶分布进行了跟踪研究。已证明在所有发育阶段,尤其是胎儿早期阶段,在所有这些组织(肝脏、肾脏、骨骼肌、大脑和心脏)中,LDH与细胞结构之间存在相当程度的相互作用。已针对这种结合的性质和程度以及与发育过程中这些组织情况的代谢重点之间的相关性对这些数据进行了讨论。

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