Bogatskaya L N, Litoshenko A Y
Vopr Med Khim. 1975 Jul-Aug;21(4):390-6.
Age alterations of the total activity and isoenzyme spectrum of lactate dehydrogenase were observed in rat skeletal muscles, liver and heart. In the aged animals the total activity of LDH was increased in skeletal and heart muscles. In the skeletal muscles and liver tissue of the aged rats content of M-subunits the LDH and the content of LDH-5 was increased. In the heart muscle content of H-subunits, LDH-1 and LDH-2 was increased as compared with adult and growing rats.
在大鼠骨骼肌、肝脏和心脏中观察到乳酸脱氢酶的总活性和同工酶谱随年龄的变化。在老年动物中，骨骼肌和心肌中乳酸脱氢酶的总活性增加。在老年大鼠的骨骼肌和肝脏组织中，乳酸脱氢酶的M亚基含量和乳酸脱氢酶-5的含量增加。与成年和生长中的大鼠相比，心肌中H亚基、乳酸脱氢酶-1和乳酸脱氢酶-2的含量增加。
