Kumar M, Kumar A M, Morgan R, Szapocznik J, Eisdorfer C
Center for Biopsychosocial Studies on AIDS, University of Miami, School of Medicine, Florida.
J Acquir Immune Defic Syndr (1988). 1993 Jan;6(1):61-5.
The corticotropin-adrenocortical response to cold pressor challenge was investigated in a study of human immunodeficiency virus (HIV) infection. Data obtained from 16 HIV-1-positive and 28 HIV-1-negative subjects are presented in this report. After the insertion of a venicatheter and following 30 min of rest, the subjects immersed one of their hands in an ice-water mixture for 2 min, and serial blood samples were obtained for the determination of ACTH and cortisol levels. The results show a significant blunting in the ACTH response and marginally lower levels of cortisol, over all time points, in HIV-1-positive subjects compared to that in HIV-1-negative subjects.
在一项关于人类免疫缺陷病毒（HIV）感染的研究中，对促肾上腺皮质激素 - 肾上腺皮质对冷加压刺激的反应进行了调查。本报告展示了从16名HIV - 1阳性和28名HIV - 1阴性受试者获得的数据。在插入静脉导管并休息30分钟后，受试者将一只手浸入冰水混合物中2分钟，并采集系列血样以测定促肾上腺皮质激素（ACTH）和皮质醇水平。结果显示，与HIV - 1阴性受试者相比，HIV - 1阳性受试者在所有时间点的ACTH反应均显著减弱，皮质醇水平略低。
