Topping D L, Illman R J, Clarke J M, Trimble R P, Jackson K A, Marsono Y
CSIRO (Australia) Division of Human Nutrition, Glenthorne Laboratory, O'Halloran Hill.
J Nutr. 1993 Jan;123(1):133-43. doi: 10.1093/jn/123.1.133.
Male pigs were fed a low fiber beef diet (control) or that diet with additional fiber either as wheat bran, oat bran or baked beans. Total large bowel digesta and volatile fatty acid (VFA) pools were highest in pigs fed the diet with baked beans, intermediate in those fed the diets with oat bran and wheat bran and lowest in those fed the control diet. In all groups digesta mass and total VFA pools rose from the cecum and then fell to the distal colon, and incremental effects of diet were the same at all sampling sites. For acetate and propionate pools there was a significant interaction between diet and anatomical site, but data conversion to logarithms abolished this interaction, indicating that all dietary effects were proportionately the same across sections. Consumption of the diets with wheat bran, oat bran and baked beans increased the total large bowel butyrate pool compared with consumption of the control diet. Digesta H+ concentrations fell along the large bowel and correlated positively with VFA concentrations in the median colon. Portal venous VFA concentrations correlated with VFA in the proximal colon only. Plasma cholesterol and biliary steroids were unrelated to portal venous propionate concentrations.
给雄性猪喂食低纤维牛肉日粮（对照），或在该日粮中添加纤维，纤维来源分别为麦麸、燕麦麸或烘豆。喂食含烘豆日粮的猪，其整个大肠消化物和挥发性脂肪酸（VFA）总量最高，喂食含燕麦麸和麦麸日粮的猪次之，喂食对照日粮的猪最低。在所有组中，消化物质量和总VFA总量从盲肠开始上升，然后在远端结肠下降，日粮的增量效应在所有采样部位相同。对于乙酸盐和丙酸盐总量，日粮与解剖部位之间存在显著交互作用，但数据转换为对数后消除了这种交互作用，表明各日粮效应在各节段中按比例相同。与喂食对照日粮相比，喂食含麦麸、燕麦麸和烘豆日粮可增加整个大肠丁酸盐总量。消化物H⁺浓度沿大肠下降，并与结肠中部的VFA浓度呈正相关。门静脉VFA浓度仅与近端结肠中的VFA相关。血浆胆固醇和胆汁类固醇与门静脉丙酸盐浓度无关。
