Topping D L, Illman R J, Taylor M N, McIntosh G H
Ann Nutr Metab. 1985;29(6):325-31. doi: 10.1159/000176989.
Adult male pigs (40-60 kg of body weight) of the Kangaroo Island strain were surgically implanted with chronic indwelling hepatic portal venous cannulae. After a 24-hour fast the animals were given meals containing 500 g of either wheat bran or porridge oats and 200 g of sucrose and 2 litres of milk. With both cereal preparations plasma volatile fatty acids rose in the hepatic portal vein but the increase was significantly greater with wheat bran. Omission of sucrose and milk did not alter the response to porridge oats but diminished the response to wheat bran. These changes in plasma volatile fatty acids were unaffected by prior cooking of the cereals with hot water. With all test meals acetate and propionate were the major acids found, with butyrate contributing less than 8% of the total. This compositional profile was also found when the pigs were fed a commercial ration. The absence of butyrate differed from observations in the rat and reflected low concentrations of this acid in large bowel digesta. The difference in the response of the concentration of volatile fatty acids to feeding porridge oats and wheat bran in the pig was also the reverse of that found in the rat. These species differences may be of significance in relation to the choice of animal models for human fibre metabolism.
成年雄性袋鼠岛品系猪（体重40 - 60千克）通过手术植入慢性留置肝门静脉插管。禁食24小时后，给这些动物喂食含有500克麦麸或燕麦片、200克蔗糖和2升牛奶的餐食。两种谷物制剂都会使肝门静脉中的血浆挥发性脂肪酸升高，但麦麸引起的升高显著更大。省略蔗糖和牛奶不会改变对燕麦片的反应，但会减弱对麦麸的反应。谷物预先用热水煮熟不会影响血浆挥发性脂肪酸的这些变化。在所有测试餐食中，乙酸和丙酸是主要发现的酸，丁酸占总量的比例不到8%。当给猪喂食商业日粮时也发现了这种组成特征。缺乏丁酸与在大鼠中的观察结果不同，这反映了大肠消化物中该酸的浓度较低。猪对喂食燕麦片和麦麸时挥发性脂肪酸浓度的反应差异也与在大鼠中发现的情况相反。这些物种差异可能与人类纤维代谢动物模型的选择具有重要关系。
