Gez E, Wygoda M, Nussbaum N, Figer A, Gil R I, Inbal M
Hadassah University Hospital, Jerusalem, Israel.
Cancer Invest. 1993;11(1):10-4. doi: 10.3109/07357909309020255.
Fourteen patients with testicular nonseminomatous germ cell tumor, clinical stage I were entered into a surveillance study. Median age was 31 (range 18-58). Three patients had pure tumor, and 11, mixed tumor. In 2 patients, vascular invasion was noted, and in 1, involvement of the spermatic cord. Serum alpha fetoprotein and beta subunit choriogonadotropin were high in 9 and in 3 patients, respectively. In median follow-up of 21 months (range 2-63), 3 patients relapsed: 1 had inguinal lymphadenopathy and 2 had lung metastases at 12, 4, and 16 months, respectively. Salvage chemotherapy PEB and PVB achieved complete response in the latter 2 patients for 6 and 49 months. Except for 1 patient lost to follow-up, all are alive.
14例临床I期睾丸非精原细胞瘤生殖细胞肿瘤患者进入一项监测研究。中位年龄为31岁（范围18 - 58岁）。3例为纯肿瘤，11例为混合肿瘤。2例患者存在血管侵犯，1例精索受累。9例和3例患者的血清甲胎蛋白和β亚单位绒毛膜促性腺激素分别升高。中位随访21个月（范围2 - 63个月），3例患者复发：1例在12个月时出现腹股沟淋巴结病，2例分别在4个月和16个月时出现肺转移。挽救性化疗PEB和PVB使后2例患者分别获得了6个月和49个月的完全缓解。除1例失访患者外，所有患者均存活。
