Kanarek R B, Hirsch E
Fed Proc. 1977 Feb;36(2):154-8.
Modifications in dietary conditions can result in small, but consistent, increases in caloric intake which over time accumulate to substantial increases in body weight. Allowing rats access to either high fat diets or a variety of highly palatable foods can lead to obesity. Recent experiments also have shown that providing access to sweet carbohydrate solutions in addition to the complete diet can cause weight gains in normal neurologically intact adult rats. Although animals increase consumption of carbohydrate on this dietary regime, they continue to maintain minimum requirements for other dietary nutrients. It appears that increasing the palatability of the diet can lead to overeating, but cannot induce the rat to select a diet that is deficient in protein, fat, vitamins, or minerals. Further exploration of the conditions associated with dietary-induced overeating in animals may provide insights into conditions related to obesity in man.
饮食条件的改变会导致热量摄入出现小幅但持续的增加，随着时间的推移，这些增加会累积为体重的显著增加。让大鼠食用高脂肪饮食或各种美味食物会导致肥胖。最近的实验还表明，除了完整的饮食外，提供甜味碳水化合物溶液也会导致正常神经系统完整的成年大鼠体重增加。尽管动物在这种饮食模式下会增加碳水化合物的摄入量，但它们仍会继续维持对其他膳食营养素的最低需求。看来增加饮食的适口性会导致暴饮暴食，但不会促使大鼠选择缺乏蛋白质、脂肪、维生素或矿物质的饮食。对与动物饮食诱导的暴饮暴食相关的条件进行进一步探索，可能会为与人类肥胖相关的条件提供见解。
