Baimaj V
Genetics. 1977 Jan;85(1):85-93. doi: 10.1093/genetics/85.1.85.
A simple technique for preparing mitotic metaphases from a larval ganglion of Drosophila is described. Parallel examination of polytene and metaphase chromosome groups shows that inversion polymorphism in chromosome 3 of D. recticilia from East Maui (Hawaii) manifests a one-to-one correlation with a metaphase karyotype polymorphism due to the presence of an extra heterochromatic portion. These observations are consistent with the previous findings on other species of Hawaiian Drosophila. They strongly support the hypothesis that when one breakpoint of a long inverted segment of a chromosome element occurs in the vicinity of the constitutive heterochromatin, it may exert an effect in eliciting the production of heterochromatic material in the same chromosome.
本文描述了一种从果蝇幼虫神经节制备有丝分裂中期相的简单技术。对多线染色体和中期染色体组的平行检查表明，来自东毛伊岛（夏威夷）的直翅果蝇3号染色体的倒位多态性与中期核型多态性呈现出一一对应的关系，这是由于存在一个额外的异染色质部分。这些观察结果与之前关于夏威夷果蝇其他物种的研究结果一致。它们有力地支持了这样一种假说，即当染色体元件的一个长倒位片段的一个断点出现在组成型异染色质附近时，它可能会在引发同一条染色体上异染色质物质的产生方面发挥作用。
