Tayler R, Cumberland V H, Piper D W
Gut. 1977 Jan;18(1):45-7. doi: 10.1136/gut.18.1.45.
Colorectal mucosa from patients with colorectal carcinoma was compared with rectal mucosa from a control group. It was found that the LDH isoenzyme pattern of uninvolved mucosa proximal and distal to the carcinoma differed from that of normal tissue and resembled that of carcinoma tissue except in the case of the uninvolved mucosa proximal to the carcinoma of the sigmoid colon, which did not differ from normal mucosa.
将结直肠癌患者的结直肠黏膜与对照组的直肠黏膜进行比较。结果发现,癌灶近端和远端未受累黏膜的乳酸脱氢酶同工酶模式与正常组织不同,且除乙状结肠癌近端未受累黏膜外,与癌组织的模式相似,而乙状结肠癌近端未受累黏膜与正常黏膜无差异。