Cameron S O, Carrington D, Patterson W
Virology Laboratory, Glasgow Royal Infirmary, U.K.
J Infect. 1993 Jan;26(1):71-4. doi: 10.1016/0163-4453(93)96904-5.
We report a major outbreak of hepatitis A enteroviral infection in an area of deprived urban housing in Glasgow. The epidemic was associated with contamination of the environment by refuse and sewage. This prompted us to investigate immunity to polioviruses. We examined samples of serum in 24 of 47 cases of hepatitis A for antibodies against polioviruses types 1, 2 and 3. Titres were satisfactory in 82%, 100% and 35% respectively. These results highlight a need for further seroepidemiological studies of immunity to polioviruses in the U.K. Recommendations are made to restrict enteroviral contamination of the environment.
我们报告了在格拉斯哥一个城市贫困住房区发生的甲型肝炎肠道病毒感染大爆发。该疫情与垃圾和污水对环境的污染有关。这促使我们对脊髓灰质炎病毒的免疫力进行调查。我们检测了47例甲型肝炎病例中24例的血清样本，以检测针对1型、2型和3型脊髓灰质炎病毒的抗体。抗体滴度分别在82%、100%和35%的样本中令人满意。这些结果凸显了在英国进一步开展脊髓灰质炎病毒免疫血清流行病学研究的必要性。同时提出了限制环境中肠道病毒污染的建议。
