美国陆军新兵对脊髓灰质炎病毒的血清免疫

Seroimmunity to polioviruses in U.S. Army recruits.

作者信息

Burke D S, Gaydos J C, Hodder R A, Bancroft W H

出版信息

J Infect Dis. 1979 Feb;139(2):225-7. doi: 10.1093/infdis/139.2.225.

DOI:10.1093/infdis/139.2.225

PMID:220335

Abstract

Titers of neutralizing antibody to poliovirus types 1, 2, and 3 were determined for serum specimens obtained from 268 U.S. Army recruits. Among those tested, 20.9% lacked neutralizing antibody to one or more types of poliovirus, and 1.1% lacked antibody to all three types. An analysis of demographic data showed that age of less than 18 years, schooling for less than 10 years, and residence in the northeastern United States were associated with higher percentages of recruits lacking neutralizing antibodies to polioviruses in serum.

摘要

对从268名美国陆军新兵采集的血清样本测定了1型、2型和3型脊髓灰质炎病毒的中和抗体滴度。在接受检测的人群中，20.9%的人缺乏针对一种或多种脊髓灰质炎病毒类型的中和抗体，1.1%的人缺乏针对所有三种类型的抗体。对人口统计学数据的分析表明，年龄小于18岁、受教育年限少于10年以及居住在美国东北部与血清中缺乏脊髓灰质炎病毒中和抗体的新兵比例较高有关。