Solomon E I, Lowery M D
Department of Chemistry, Stanford University, CA 94305.
Science. 1993 Mar 12;259(5101):1575-81. doi: 10.1126/science.8384374.
Many metalloenzymes exhibit distinctive spectral features that are now becoming well understood. These reflect active site electronic structures that can make significant contributions to catalysis. Copper proteins provide well-characterized examples in which the unusual electronic structures of their active sites contribute to rapid, long-range electron transfer reactivity, oxygen binding and activation, and the multielectron reduction of dioxygen to water.
许多金属酶表现出独特的光谱特征，如今人们对这些特征已有了深入的了解。这些特征反映了活性位点的电子结构，而这种结构能够对催化作用做出重大贡献。铜蛋白提供了特征明确的例子，其中活性位点不同寻常的电子结构有助于快速的长程电子转移反应、氧的结合与活化，以及将双氧多电子还原为水。
