van der Kolk J H, van der Wijden M W, Jongejan F
Vakgroep Inwendige Zieketen en Voeding der Grote Huisdieren, Faculteit Diergeneeskunde, Utrecht.
Tijdschr Diergeneeskd. 1993 Apr 1;118(7):227-9.
Equine granulocytic ehrlichiosis (EGE) has been observed in the U.S.A., Brazil, Germany, Sweden, Switzerland and possibly in Great Britain. The causative agent is rickettsia Ehrlichia equi, identified for the first time in 1969. The clinical features of the disease are anorexia, fever, depression, (limb) oedema, icterus, ataxia, petechiae and orchitis. Hematologic changes are leukopenia, thrombocytopenia, anemia and cytoplasmic inclusion bodies in the neutrophils and eosinophils. Vasculitis may be observed at autopsy. Following a positive hematological diagnosis (Giemsa stained blood smear) of EGE, treatment with oxytetracycline can be initiated.
马粒细胞埃立克体病(EGE)已在美国、巴西、德国、瑞典、瑞士被观察到,在英国可能也有发生。病原体是埃立克体属马埃立克体,于1969年首次被鉴定。该病的临床特征为厌食、发热、抑郁、(肢体)水肿、黄疸、共济失调、瘀点和睾丸炎。血液学变化包括白细胞减少、血小板减少、贫血以及中性粒细胞和嗜酸性粒细胞中的细胞质包涵体。尸检时可能观察到血管炎。在对EGE进行血液学阳性诊断(吉姆萨染色血涂片)后,可开始用土霉素进行治疗。