Nolen-Walston Rose D, D'Oench Sarah M, Hanelt Lisa M, Sharkey Leslie C, Paradis Mary Rose
Hospital for Large Animals, School of Veterinary Medicine, Tufts University, North Grafton, MA 01536, USA.
J Am Vet Med Assoc. 2004 Jun 15;224(12):1964-6, 1931.
An 11-year-old Hanoverian-cross gelding was evaluated because of acute onset of ataxia, recumbency, and fever. At the stable, this and other horses had recently been infested with ticks. Results of analysis of a sample of CSF were within reference limits, but hematologic abnormalities included lymphopenia, thrombocytopenia, mild anemia, and intracytoplasmic inclusion bodies in neutrophils that were consistent with Anaplasma phagocytophilum (previously Ehrlichia equi). Results of serum biochemical analyses were characteristic of infection and included high, unconjugated bilirubin concentration. Other common causes of recumbency in horses, such as equine protozoal myeloencephalitis, infection with eastern or western equine encephalitis viruses and equine herpesvirus-1, West Nile viral encephalitis, trauma, and metabolic disease, were ruled out. The horse responded quickly to i.v. administration of oxytetracycline and recovered fully within 6 days.
一匹11岁的汉诺威杂交阉马因急性共济失调、卧地不起和发热接受评估。在马厩里,这匹马和其他马匹最近感染了蜱虫。脑脊液样本分析结果在参考范围内,但血液学异常包括淋巴细胞减少、血小板减少、轻度贫血以及中性粒细胞内的胞质内包涵体,与嗜吞噬细胞无形体(以前的马埃立克体)一致。血清生化分析结果具有感染特征,包括高浓度的未结合胆红素。其他导致马匹卧地不起的常见原因,如马原生动物脑脊髓炎、东部或西部马脑炎病毒感染、马疱疹病毒1型、西尼罗河病毒性脑炎、创伤和代谢性疾病,均被排除。这匹马对静脉注射土霉素反应迅速,6天内完全康复。