Close P M, Macrae M B, Hammond J M, Aronson I, Johnson C A, Potgieter P D, Jacobs P
Department of Anatomical Pathology, University of Cape Town, South Africa.
Am J Clin Pathol. 1993 May;99(5):631-6. doi: 10.1093/ajcp/99.5.631.
An unusual presentation of anaplastic large-cell (ALC) Ki-1 lymphoma is described, in which pulmonary involvement mimicked miliary tuberculosis. Lung involvement is uncommon in this type of lymphoma, and it is not clear from previous reports whether this was a presenting feature. Bone marrow involvement, rare in Ki-1 lymphoma, also was present in this case. Despite therapy skin involvement subsequently developed, and the patient died 3 months after presentation. Postmortem examination revealed lymphomatous involvement of the heart, liver, kidneys, stomach, and lymph nodes. This case highlights the need for awareness of ALC Ki-1 lymphoma particularly when it presents at uncommon extranodal sites.
