Black K, Hanna S S, Langer B, Jirsch D W, Rider W D
Can J Surg. 1978 Nov;21(6):542-5.
The records of 80 cases of carcinoma of the extrahepatic bile ducts were studied. The median duration of survival, in months, of patients who were treated by curative surgery, palliative surgery and radiation, palliative surgery alone and biopsy alone was 21.7, 9.3, 5.5 and 1, respectively. The best results were obtained by excision of the tumour, but only 10% of tumours were considered resectable. A more aggressive surgical approach to tumours still confined to the bile ducts might be expected to increase the resectability rate and improve survival. The use of a U tube is recommended because it ensures greater comfort even though survival is no longer than when a T tube is used. The roles of adjuvant radiotherapy and chemotherapy need further study. Because of some encouraging responses with the use of radiotherapy and the infusion of 5-fluorouracil the authors are currently evaluating these two methods of treatment.
对80例肝外胆管癌病例的记录进行了研究。接受根治性手术、姑息性手术加放疗、单纯姑息性手术及单纯活检的患者，其生存时间中位数（以月为单位）分别为21.7、9.3、5.5和1。切除肿瘤可获得最佳结果，但仅10%的肿瘤被认为可切除。对于仍局限于胆管的肿瘤，采用更积极的手术方法有望提高可切除率并改善生存率。推荐使用U形管，因为尽管其生存时间并不长于使用T形管时，但能确保患者更舒适。辅助放疗和化疗的作用尚需进一步研究。鉴于放疗及输注5-氟尿嘧啶取得了一些令人鼓舞的疗效，作者目前正在评估这两种治疗方法。
