编码核衣壳蛋白的基因：3型鼠肝炎病毒的序列分析及冠状病毒科的进化
The gene encoding the nucleocapsid protein: sequence analysis in murine hepatitis virus type 3 and evolution in Coronaviridae.
作者信息
Décimo D, Philippe H, Hadchouel M, Tardieu M, Meunier-Rotival M
机构信息
INSERM Unité 347 affiliée au CNRS, Université Paris XI, Hôpital de Kremlin-Bicêtre, France.
出版信息
Arch Virol. 1993;130(3-4):279-88. doi: 10.1007/BF01309660.
Abstract
The nucleoprotein-encoding gene (N) of murine hepatitis virus type 3 (MHV 3), from the Mill Hill strain, was cloned and sequenced. It was compared to gene N from other murine coronaviruses and was found to share more similarities with N sequences from MHV 1 and MHV JHM strains than with the published MHV 3 N sequence which is almost identical to MHV A59. We suggest that the evolution of some MHV N sequences resulted from a double recombination phenomenon between two ancestors. Furthermore, comparison of protein N from avian and mammalian coronaviruses leads to the hypothesis that horizontal transfer events of the virus from one host species to another have occurred.
摘要
对米尔希尔株3型鼠肝炎病毒（MHV 3）的核蛋白编码基因（N）进行了克隆和测序。将其与其他鼠冠状病毒的N基因进行比较，发现它与MHV 1和MHV JHM株的N序列相比，与已发表的几乎与MHV A59相同的MHV 3 N序列有更多相似性。我们认为，一些MHV N序列的进化是由两个祖先之间的双重重组现象导致的。此外，对禽冠状病毒和哺乳动物冠状病毒的N蛋白进行比较，得出了病毒从一种宿主物种向另一种宿主物种发生水平转移事件的假说。
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本文引用的文献
1
Sequence of the nucleocapsid gene from murine coronavirus MHV-A59.鼠冠状病毒MHV - A59核衣壳基因序列
Nucleic Acids Res. 1983 Feb 11;11(3):883-91. doi: 10.1093/nar/11.3.883.
2
The molecular biology of coronaviruses.冠状病毒的分子生物学
Adv Virus Res. 1983;28:35-112. doi: 10.1016/s0065-3527(08)60721-6.
3
Coronavirus JHM: nucleotide sequence of the mRNA that encodes nucleocapsid protein.冠状病毒JHM：编码核衣壳蛋白的mRNA的核苷酸序列。
Nucleic Acids Res. 1983 Aug 11;11(15):5045-54. doi: 10.1093/nar/11.15.5045.
4
Ependymitis, leukoencephalitis, hydrocephalus, and thrombotic vasculitis following chronic infection by mouse hepatitis virus 3 (MHV 3).小鼠肝炎病毒3型（MHV 3）慢性感染后的室管膜炎、白质脑炎、脑积水和血栓性血管炎。
Acta Neuropathol. 1982;58(3):168-76. doi: 10.1007/BF00690797.
5
Isolation of coronavirus envelope glycoproteins and interaction with the viral nucleocapsid.冠状病毒包膜糖蛋白的分离及其与病毒核衣壳的相互作用。
J Virol. 1980 Jan;33(1):449-62. doi: 10.1128/JVI.33.1.449-462.1980.
6
Efficient isolation of genes by using antibody probes.使用抗体探针高效分离基因。
Proc Natl Acad Sci U S A. 1983 Mar;80(5):1194-8. doi: 10.1073/pnas.80.5.1194.
7
The biology and pathogenesis of coronaviruses.冠状病毒的生物学特性与发病机制。
Curr Top Microbiol Immunol. 1982;99:165-200. doi: 10.1007/978-3-642-68528-6_5.
8
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9
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Gene. 1988 Dec 15;73(1):237-44. doi: 10.1016/0378-1119(88)90330-7.
10
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J Gen Virol. 1988 Dec;69 ( Pt 12):2939-52. doi: 10.1099/0022-1317-69-12-2939.
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