Torkko H, Asikainen S
Oral Microbiology Service Laboratory, University of Helsinki, Finland.
FEMS Immunol Med Microbiol. 1993 Mar;6(2-3):195-8. doi: 10.1111/j.1574-695X.1993.tb00325.x.
To further examine the previously suggested inverse relationship between Porphyromonas gingivalis and Prevotella intermedia in periodontal disease, 1016 samples taken from single or multiple (pooled) subgingival sites were cultured anaerobically and examined for the simultaneous occurrence of the microorganisms. P. gingivalis was isolated from 297 (29%) and Pr. intermedia from 501 (49%) samples. P. gingivalis was found as frequently with (14%) as without (15%) Pr. intermedia. The type of sampling had no effect on the occurrence of P. gingivalis with Pr. intermedia. However, female subjects harboured them in combination more frequently than male subjects. The mean proportions of P. gingivalis in the cultivable flora appeared to be lower when found with than without Pr. intermedia. Whether the detection of the combination, or P. gingivalis alone, has clinical relevance needs further clarification.
为进一步研究先前提出的牙周病中牙龈卟啉单胞菌与中间普氏菌之间的负相关关系，对取自单个或多个（混合）龈下部位的1016份样本进行厌氧培养，并检测这两种微生物的同时存在情况。297份（29%）样本分离出牙龈卟啉单胞菌，501份（49%）样本分离出中间普氏菌。牙龈卟啉单胞菌与中间普氏菌同时存在的情况占14%，未同时存在的情况占15%，两者出现频率相近。采样类型对牙龈卟啉单胞菌与中间普氏菌同时存在的情况没有影响。然而，女性受试者同时携带这两种菌的频率高于男性受试者。与未同时存在中间普氏菌相比，可培养菌群中牙龈卟啉单胞菌的平均比例在同时存在时似乎更低。同时检测到这两种菌或仅检测到牙龈卟啉单胞菌是否具有临床相关性，还需要进一步阐明。
