Teneberg S, Willemsen P T, de Graaf F K, Karlsson K A
Department of Medical Biochemistry, University of Gothenburg, Sweden.
FEMS Microbiol Lett. 1993 May 1;109(1):107-12. doi: 10.1111/j.1574-6968.1993.tb06151.x.
Non-acid and acid glycolipids were isolated from the small intestine of a newborn calf and tested for the ability to bind Escherichia coli carrying K99 fimbriae. The bacteria did not bind to any of the non-acid glycolipids, whereas in the acid glycolipid fraction several gangliosides were detected which bind to K99 fimbriae. Gangliosides capable of binding K99 fimbriated E. coli were characterized as NeuGc-GM3, NeuGc-GM2, NeuGc-GD1a NeuAc-SPG and NeuAc-SPG. No binding was detected to NeuAc-GM3 and NeuGc-GM1.
从新生小牛的小肠中分离出非酸性和酸性糖脂，并测试其结合携带K99菌毛的大肠杆菌的能力。这些细菌不与任何非酸性糖脂结合，而在酸性糖脂部分检测到几种与K99菌毛结合的神经节苷脂。能够结合K99菌毛化大肠杆菌的神经节苷脂被鉴定为NeuGc-GM3、NeuGc-GM2、NeuGc-GD1a、NeuAc-SPG和NeuAc-SPG。未检测到与NeuAc-GM3和NeuGc-GM1的结合。
