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对一株天然存在的不产生K99的K99+产肠毒素大肠杆菌菌株的分析。

Analysis of a naturally occurring K99+ enterotoxigenic Escherichia coli strain that fails to produce K99.

作者信息

Isaacson R E, Patterson S

机构信息

Department of Veterinary Pathobiology, University of Illinois, Urbana 61801.

出版信息

Infect Immun. 1994 Oct;62(10):4686-9. doi: 10.1128/iai.62.10.4686-4689.1994.

DOI:10.1128/iai.62.10.4686-4689.1994
PMID:7927743
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC303168/
Abstract

A spontaneously occurring field isolate of enterotoxigenic Escherichia coli that was genotypically K99+ but phenotypically K99- was analyzed for the reason that it did not express K99. The defect, which was cis active, was located within an area 5' to the first gene required for K99 biogenesis and was the result of the deletion of a single base pair.

摘要

对一株基因型为K99+但表型为K99-的产肠毒素大肠杆菌自发分离株进行了分析，原因是它不表达K99。该缺陷具有顺式活性，位于K99生物合成所需的第一个基因5'端的一个区域内，是单个碱基对缺失的结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b91/303168/201f3b7fa810/iai00010-0601-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b91/303168/201f3b7fa810/iai00010-0601-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b91/303168/201f3b7fa810/iai00010-0601-a.jpg

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本文引用的文献

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Calf small intestine receptors for K99 fimbriated enterotoxigenic Escherichia coli.K99菌毛产肠毒素大肠杆菌的犊牛小肠受体
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Transcriptional organization of the Escherichia coli pilus adhesin K99.大肠杆菌菌毛黏附素K99的转录组织
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Regulation of expression of Escherichia coli pilus K99.大肠杆菌K99菌毛表达的调控
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Biochemical comparison of pili from variants of Neisseria gonorrhoeae P9.淋病奈瑟菌P9变种菌毛的生化比较
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Prevalence of pilus antigens, enterotoxin types, and enteropathogenicity among K88-negative enterotoxigenic Escherichia coli from neonatal pigs.新生仔猪K88阴性产肠毒素大肠杆菌中菌毛抗原、肠毒素类型及肠致病性的流行情况
Infect Immun. 1980 Jan;27(1):222-30. doi: 10.1128/iai.27.1.222-230.1980.