Alison M R, Wright N A
Department of Histopathology, Royal Postgraduate Medical School, Hammersmith Hospital, London.
Br J Hosp Med. 1993;49(11):774-5, 778, 781-3 passim.
Peptide growth factors and their cell surface-associated receptors are important determinants of normal and pathological growth reactions. Through signal transduction pathways, receptor occupancy triggers the production of intracellular downstream effector molecules which ultimately cause cell proliferation.
肽生长因子及其细胞表面相关受体是正常和病理生长反应的重要决定因素。通过信号转导途径,受体占据会触发细胞内下游效应分子的产生,这些分子最终导致细胞增殖。