氨茶碱的生物利用度及血浆茶碱水平随时间的稳定性。
Aminophylline bioavailability and the across-time stability of plasma theophylline levels.
作者信息
Loren M, Miklich D R, Chai H, Barwise G
出版信息
J Pediatr. 1977 Mar;90(3):473-6. doi: 10.1016/s0022-3476(77)80719-1.
PMID:839342
Abstract
Three generic aminophylline products were examined and found to have equivalent bioavailability. Plasma theophylline levels were found to be reproducible in most patients (intraclass r = 0.7). There were some patients who showed wide swings in plasma theophylline levels without signs of toxicity or clinical deterioration.
摘要
对三种普通氨茶碱产品进行了检测，发现它们具有等效的生物利用度。在大多数患者中，血浆茶碱水平具有可重复性（组内相关系数r = 0.7）。有一些患者血浆茶碱水平波动很大，但没有毒性迹象或临床病情恶化。
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