Escher J, Höhmann U, Anthenien L, Dayer E, Bosshard C, Gaillard R C
Internmedizinische Abteilung, Oberwalliser Kreisspital Brig.
Schweiz Med Wochenschr. 1993 Jul 3;123(26):1354-8.
As part of a project "Music therapy in internal medicine" we investigated 32 consecutive patients undergoing gastroscopy for various reasons. Patients were randomly assigned to two groups, regardless of sex, age or underlying disease. One group listened to music during gastroscopy, while the other did not. The choice of the type of music within the corresponding group was made with the patient and a trained music therapist in a short discussion prior to gastroscopy. The hormones ACTH and cortisol, as well as the catecholamines adrenalin and noradrenaline, were measured in both groups with three blood samples taken before, directly after and one hour after gastroscopy. Parallel measurements included blood pressure and pulse rate as well as questions about the patients' feelings during gastroscopy. The study showed the rise in the plasma levels of the stress hormones ACTH and cortisol to be significantly lower under the influence of music. The subjective feelings of the patients concerning "fear in general" and "fear about gastroscopy" paralleled these findings. Conversely, the plasma adrenalin and noradrenaline levels before and after gastroscopy were virtually unchanged in both groups, as were pulse rate and blood pressure. This study shows the influence of music on human biochemical parameters when used in the setting of a diagnostic procedure.
作为“内科音乐疗法”项目的一部分，我们对32例因各种原因接受胃镜检查的连续患者进行了调查。患者被随机分为两组，不考虑性别、年龄或基础疾病。一组在胃镜检查期间听音乐，而另一组不听。在相应组内音乐类型的选择是在胃镜检查前与患者和一名经过培训的音乐治疗师进行简短讨论后确定的。两组均在胃镜检查前、检查后即刻和检查后一小时采集三份血样，检测促肾上腺皮质激素（ACTH）、皮质醇以及儿茶酚胺肾上腺素和去甲肾上腺素等激素。同时测量包括血压和脉搏率，以及询问患者在胃镜检查期间的感受。研究表明，在音乐的影响下，应激激素ACTH和皮质醇的血浆水平升高明显较低。患者关于“总体恐惧”和“对胃镜检查的恐惧”的主观感受与这些发现一致。相反，两组胃镜检查前后的血浆肾上腺素和去甲肾上腺素水平几乎没有变化，脉搏率和血压也是如此。这项研究表明了音乐在诊断程序中使用时对人体生化参数的影响。
