Paulus W, Jellinger K, Hallas C, Ott G, Müller-Hermelink H K
Institute of Pathology, University of Würzburg, Germany.
Neurology. 1993 Aug;43(8):1591-3. doi: 10.1212/wnl.43.8.1591.
Using dot blotting, we found Epstein-Barr virus genome in three AIDS-related primary cerebral lymphomas (PCLs), but in none of 39 sporadic PCLs. Human herpesvirus-6 sequences were present only in one sporadic PCL, as revealed by polymerase chain reaction and Southern analysis. We conclude that these viruses do not appear to play a major role in PCL pathogenesis in immunocompetent subjects.