Burch W M
Department of Medicine and Clinical Science, J.C.S.M.R., Australian National University, Canberra.
Nucl Med Commun. 1993 Jul;14(7):559-61. doi: 10.1097/00006231-199307000-00007.
Technegas is a suspension of structured graphite ellipsoids, between 5 and 20 nm in aerodynamic diameter and labelled, in a carrier gas of argon, with 99Tcm. Its emergence and rapidly expanding clinical usage (105,000 studies, 22 countries), as a unique dry insoluble microaerosol for diagnostic lung imaging, has prompted a review of reports of experiments on lung clearance with other aerosols. No direct comparison exists although it is clear that experimental inhalation insults which deliver to the alveoli a mass of material orders of magnitude greater than Technegas are well tolerated by human volunteers.
锝气体是一种由结构石墨椭球体组成的悬浮液,其空气动力学直径在5至20纳米之间,在氩载气中用99锝标记。作为一种用于诊断性肺部成像的独特干燥不溶性微气溶胶,它的出现及其临床应用的迅速扩展(涉及22个国家的105000项研究)促使人们对其他气溶胶肺部清除实验的报告进行了回顾。尽管很明显,向肺泡输送的物质质量比锝气体大几个数量级的实验性吸入刺激,人类志愿者能够很好地耐受,但目前尚无直接比较。