Kurita K, Yoshida A, Tanabe G, Shirao K, Hamanoue M, Aikou T, Shimazu H
First Department of Surgery, Faculty of Medicine, Kagoshima University, Japan.
Surg Today. 1993;23(6):528-31. doi: 10.1007/BF00730629.
We would like to draw attention to hepatic tumor-like lesions which frequently complicate the differential diagnosis of hepatocellular carcinoma (HCC), while considering their pathology and diagnosis by radiographic imaging. In particular, adenomatous hyperplasia is recognized as a precancerous lesion of HCC, and the relationship between adenomatous hyperplasia and the multicentric development of HCC is recognized. We observed a patient who demonstrated hyperplastic changes in both the liver cells and a well-differentiated HCC lesion adjacent to the adenomatous hyperplasia, suggesting a multicentric development of the HCC. The histopathological features of adenomatous hyperplasia are also described.